Published January 2016 | Version v1
Journal article Metadata-only

Marrow damage and hematopoietic recovery following allogeneic bone marrow transplantation for acute leukemias: Effect of radiation dose and conditioning regimen

Creators

  • 1. Dept. of Therapeutic Radiology, University of Minnesota, Minneapolis (United States)
  • 2. Dept. of Medicine, University of Minnesota, Minneapolis (United States)
  • 3. Veterinary Clinical Sciences, University of Minnesota, Minneapolis (United States)
  • 4. Biostatistics Core, Masonic Cancer Center, University of Minnesota, Minneapolis (United States)
  • 5. Masonic Cancer Center, University of Minnesota, Minneapolis (United States)
  • 6. Laboratory Medicine/Pathology, University of Minnesota, Minneapolis (United States)
  • 7. Dept. of Radiation Oncology, IRCCS San Martino-National Institute for Cancer Research and University of Genoa Largo R (Italy)
  • 8. College of Pharmacy, University of Arkansas for Medical Sciences (United States)
  • 9. College of Medicine, Oklahoma Health Sciences Center (United States)
  • 10. Dept. of Radiation Oncology, Saint-Herblain Cédex (France)
  • 11. Dept. of Radiotherapy, Universitair Ziekenhuis Brussel (Belgium)
  • 12. Div. of Hematology, Oncology and Bone Marrow Transplantation, Dept. of Pediatrics, University of Minnesota, Minneapolis (United States)

Description

Background and purpose: Total body irradiation (TBI) is a common component of hematopoietic cell transplantation (HCT) conditioning regimens. Preclinical studies suggest prolonged bone marrow (BM) injury after TBI could contribute to impaired engraftment and poor hematopoietic function.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.radonc.2015.11.012

Additional details

Identifiers

DOI
10.1016/j.radonc.2015.11.012;
PII
S0167814015006179;

Publishing Information

Journal Title
Radiotherapy and Oncology
Journal Volume
118
Journal Issue
1
Journal Page Range
p. 65-71
ISSN
0167-8140
CODEN
RAONDT

INIS

Country of Publication
Ireland
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
50080925
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BIOLOGICAL RECOVERY; BONE MARROW; INJURIES; LEUKEMIA; RADIATION DOSES; WHOLE-BODY IRRADIATION
Descriptors DEC
ANIMAL TISSUES; BODY; DISEASES; DOSES; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; IMMUNE SYSTEM DISEASES; IRRADIATION; NEOPLASMS; ORGANS

Optional Information

Copyright
Copyright (c) 2017 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.