Radiation-sterilization of frozen biostatic grafts by means of an electron accelerator

Optimal conditions for radiation sterilization of frozen transplants were determined. When using on 10 MeV electron accelerator the thickness of different transplants should not exceed the following values: 15 mm for compact bone, 25 mm for spongy bone, 50 mm for lyophilized fibrous connective tissue transplants and 20 mm for hydrated connective tissue transplants. The temperature rise in the samples during sterilization does not exceed critical value. Freezing of tissues before and during radiation sterilization has a certain protective effect in respect to tissue proteins. (author)