Published July 1981 | Version v1
Journal article

Effect of cis-dichlorodiammine platinum II and x rays on mammalian cell survival

  • 1. Institut Gustave-Roussy, Villejuif, France

Description

Incubation with cis dichlorodiammine platinum II for 1 hour prior to x-irradiation decreases the survival of rat hepatoma (H4) cells irradiated in plateau phase. The drug is more effective when the cells are irradiated in hypoxia. However, cis-Pt (II) does not affect the Do of exponetially growing H4 cells. The repair of sublethal and of potentially lethal damage are inhibited by the drug

Additional details

Publishing Information

Journal Title
Int. J. Radiat. Oncol., Biol. Phys.
Journal Volume
7
Journal Issue
7
Series
Int. J. Radiat. Oncol., Biol. Phys.
Journal Page Range
929-933
ISSN
0360-3016