Simultaneous transcatheter therapy of perimembranous ventricular septal defect combined with atrial septal defect

Objective: To evaluate the possibility, methods and efficiency of simultaneous transcatheter therapy for perimembranous ventricular septal defect (PMVSD) combined with atrial septal defect (ASD). Methods: Four patients with PMVSD combined with ASD, including 3 males and 1 female, age ranging from 12 to 26 years; underwent simultaneous attempted transcatheter therapy. The diameters of PMVSD were 3 - 6 mm and the distances from the defect rim to aortic valve were 2 - 6 mm by the echocardiography before the precedure. The stretched diameter of ASD was 6 - 10 mm. PMVSD were occluded using homemade two-disc PMVSD occluder first and the ASD were occluded later on. Results: All patients were treated successfully at one time. The diameter of PMVSD were 3.5 - 10.0 mm, the diameters of occluder was 4 - 12 mm. The stretched diameter of ASD was 6 - 10 mm and the occluder diameter was 6 - 12 mm. No residual shunt was found by the transthoracic echocardiography and left ventriculography after the occluders deployed. No complication occurred. Conclusion: Simultaneous transcatheter therapy for PMVSD combined with ASD is feasible, safe and effective. (authors)