Contamination, source and potential risks of pharmaceuticals and personal products (PPCPs) in Baiyangdian Basin, an intensive human intervention area, China

Highlights: • 30 PPCPs were frequently detected with seasons in water from the Baiyangdian Basin. • The integrated source identification showed domestic sewage was main PPCPs output. • The predominant PPCPs showed relatively high risk via semi-probabilistic approach. • Intensive human intervention proved effective in the alleviation of PPCPs pollution. The presence of pharmaceuticals and personal care products (PPCPs) has become a global concern, as it poses a threat to the environment, especially to the aquatic ecosystem. This study focused on 30 PPCPs found in the Baiyangdian basin of the Xiong'an New Area, in the core of Beijing-Tianjin-Hebei region, with intensive human interventions during two seasons. In general, 30 PPCPs were all frequently detected, ranging from 42.3 to 7710 ng/L in May and 48.9 to 1300 ng/L in November. Sulfamethoxazole, ofloxacin, anhydro-erythromycin, carbamazepine, caffeine, and were screened as the predominant PPCPs. The rivers input was an essential source of PPCPs. The source apportionment with a series of analytical methods revealed that domestic sewage was the primary source, and untreated water also crucial for PPCPs contamination. The risk assessment suggested carbamazepine, caffeine, ofloxacin, and anhydro-erythromycin exhibited relatively high ecological risks for protecting most species such as algae, fish, and flowers in the aquatic ecosystem, especially near the outlet of WWTPs. Thus, management strategies for such PPCPs will be needed. Intensive human interventions, including a prohibition of fish breeding, water diversion project, and wastewater treatment in villages, were having an effective role in alleviating PPCPs contamination.