Synthesis Of Gold Nanoparticles By Gamma Irradiation Method Using Hyaluronan As Stabilizer

Gold nanoparticles (AuNPs) with diameter from 4 to 10 nm were synthesized in hyaluronan (HA) solution without usage of any reductant and *OH radical scavenger by gamma irradiation reduction. The size and size distribution of AuNPs were determined by TEM images. The λmax (517 - 525 nm) of colloidal AuNPs solutions as prepared was measured by UV-Vis spectroscopy. The influence factors on the size of AuNPs particularly the concentration of Au3+, HA and dose rate were investigated. The stability of AuNPs/HA as synthesized was more than 6 months in storage under ambient condition. AuNPs with the size less than 10 nm and narrow size distribution stabilized by HA is biocompatible so that AuNPs/HA can potentially be applied in biomedicine and cosmetic. (author)