Diagnosis in medullary thyroid cancer with [18F]FDG-PET and improvement using a combined PET/CT scanner
- 1. Department of Nuclear Medicine, University of Esses (Germany)
- 2. Department of Radiodiagnostics, University of Essen (DE)
Description
Today, positron emission tomography (PET) investigation using fluorodeoxyglucose (FDG) is the most sensitive and specific single modality established for localizing metastases of medullary thyroid cancer (MTC). Even at calcitonin serum levels below 20 pg/ml, tumor localization may be successful in individual cases. However, especially in such early tumor stages, the morphological correlation using PET is unsatisfactory. With the newly available fixed combination of PET and computed tomography (PET/CT), this drawback can be overcome as PET/CT allows a point-by-point correlation of pathological function with morphological structure. Conventional PET alone yielded an approx 80 % sensitivity and specificity in MTC: a result that will be surpassed by the combined PET/CT scanner. (author)
Additional details
Publishing Information
- Journal Title
- Acta Medica Austriaca
- Journal Volume
- 30
- Journal Page Range
- p. 22-25
- ISSN
- 0303-8173
INIS
- Country of Publication
- Austria
- Country of Input or Organization
- Austria
- INIS RN
- 34078347
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CALCITONIN; CARCINOMAS; COMPUTERIZED TOMOGRAPHY; DIAGNOSIS; FLUORINE 18; FLUORODEOXYGLUCOSE; GLUCOSE; METABOLISM; POSITRON COMPUTED TOMOGRAPHY; RADIOISOTOPE SCANNERS; SENSITIVITY; SPECIFICITY; THYROID
- Descriptors DEC
- ALDEHYDES; ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; ENDOCRINE GLANDS; FLUORINE ISOTOPES; GLANDS; HEXOSES; HORMONES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; MONOSACCHARIDES; NANOSECONDS LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PEPTIDES; POLYPEPTIDES; PROTEINS; RADIOISOTOPES; SACCHARIDES; TOMOGRAPHY