Published March 1986 | Version v1
Journal article Metadata-only

Radiation-cytogenetic study of the mechanism of formation of chromosome aberations in Crepis capillaris cells

Creators

  • 1. AN SSSR, Moscow. Inst. Khimicheskoj Fiziki
  • 2. Moskovskij Inzhenerno-Fizicheskij Inst. (USSR)

Description

Incomplete chromatid exchanges induced by γ-quanta at G2 stage of Crepis capillaris meristem cells are transformed into complete chromosome exchanges during the second nuclear cycle. After the combined effect of γ-quanta and DNA synthesis inhibitor 5-fluoro-2-deoxyridine, the exchange aberrations disappear. During the second nuclear cycle, the chromatid exchanges, which were not realized in the presence of 5-fluro-2-deoxyuridne and regarded as potential ones, are transformed into chromosome exchanges. The breaks induced by 5-fluoro-2-deoxyuridine at G2 stage are repaired after one nuclear cycle

Additional details

Additional titles

Subtitle (English)
Reproduction of aberrations induced at G_2 stage by gamma-quanta 5-fluoro-2-desoxyuridine and at their combined action during second nuclear cycle
Original title (Russian)
Radiatsionno-tsitogeneticheskij analiz mekhanizma formirovaniya aberratsij khromosom v kletkakh Crepis capillaris
Original subtitle (Russian)
Reproduktsiya aberratsij, indutsirovannykh v G_2-faze #gamma#-kvantami, 5-ftor-2-dezoksiuridinom i pri ikh sovmestnom dejstvii, vo vtorom yadernom tsikle.

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
26
Journal Issue
2
Series
Radiobiologiya.
Journal Page Range
175-179
ISSN
0033-8192
CODEN
RADOA

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
18005457
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOSYNTHESIS; CELL NUCLEI; CHROMOSOMAL ABERRATIONS; COBALT 60; CREPIS; DNA; FUDR; GENETIC RADIATION EFFECTS; INHIBITION; MERISTEMS; MITOSIS
Descriptors DEC
ANTIBIOTICS; ANTIMETABOLITES; AZINES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CELL CONSTITUENTS; CELL DIVISION; COBALT ISOTOPES; DRUGS; FLUOROURACILS; GENETIC EFFECTS; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MINUTES LIVING RADIOISOTOPES; MUTATIONS; NUCLEI; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANIC FLUORINE COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PLANT TISSUES; PLANTS; PYRIMIDINES; RADIATION EFFECTS; RADIOISOTOPES; RADIOSENSITIZERS; RESPONSE MODIFYING FACTORS; RIBOSIDES; SYNTHESIS; URACILS; YEARS LIVING RADIOISOTOPES