Published 2003 | Version v1
Report Metadata-only

Utilization of the IEA-R1 reactor for DNA irradiation

Creators

  • 1. Instituto Superior de Ciencias y Tecnologias Nucleares (ISCTN), Havana (Cuba)
  • 2. Instituto Superior de Ciencias y Tecnologias Nucleares (ISCTN), Havana (CU)
  • 3. Instituto de Fisica, Universidad de Sao Paulo (IFUSP) (BR)
  • 4. Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN/SP) (BR)

Description

Full text: The Beam Hole no.3(BHno.3) of the IEA-R1 Reactor of IPEN-CNEN, Sao Paulo was designed for research in Boron Neutron Capture Therapy (BNCT). This facility will be used for study of radiation-induced DNA damage. The increasing knowledge of the cellular response to radiation damage has contributed to further improvements in radiation therapy. In order to reduce the gamma contamination and have sufficient neutron fluxes for irradiation of DNA molecule, it will be necessary to collocate several neutron filters in the beam hole. The choice of the adequate filter arrangement was carried with Monte Carlo-4B code. Our propose is to irradiate DNA molecule with thermal, epithermal and fast neutron from BNCT Research facility at the IEA-R1m reactor. The obtained results of simulation will be shown in this paper. (author)

Part of:
International conference on research reactor utilization, safety, decommissioning, fuel and waste management. Extended synopses

Additional details

Publishing Information

Imprint Title
International conference on research reactor utilization, safety, decommissioning, fuel and waste management. Extended synopses
Imprint Pagination
231 p.
Journal Page Range
p. 85
Report number
IAEA-CN--100

Conference

Title
International conference on research reactor utilization, safety, decommissioning, fuel and waste management
Dates
10-14 Nov 2003
Place
Santiago (Chile)

INIS

Country of Publication
International Atomic Energy Agency (IAEA)
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
35015559
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE; S21: SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BEAM HOLES; BIOLOGICAL RADIATION EFFECTS; DNA; EPITHERMAL NEUTRONS; FAST NEUTRONS; IEAR-1 REACTOR; MONTE CARLO METHOD; NEUTRON CAPTURE THERAPY; NEUTRON FLUX; RADIOTHERAPY; THERMAL NEUTRONS
Descriptors DEC
BARYONS; BIOLOGICAL EFFECTS; CALCULATION METHODS; ELEMENTARY PARTICLES; ENRICHED URANIUM REACTORS; FERMIONS; HADRONS; MEDICINE; NEUTRON THERAPY; NEUTRONS; NUCLEAR MEDICINE; NUCLEIC ACIDS; NUCLEONS; ORGANIC COMPOUNDS; POOL TYPE REACTORS; RADIATION EFFECTS; RADIATION FLUX; RADIOLOGY; RADIOTHERAPY; REACTOR CHANNELS; REACTOR COMPONENTS; REACTOR EXPERIMENTAL FACILITIES; REACTORS; RESEARCH AND TEST REACTORS; RESEARCH REACTORS; THERAPY; THERMAL REACTORS; WATER COOLED REACTORS; WATER MODERATED REACTORS

Optional Information

Secondary number(s)
IAEA-CN--100/57P