Published 1975 | Version v1
Journal article Metadata-only

Augmentation of cytotoxic drug action and x-irradiation by antibodies

Creators

  • 1. Imperial Cancer Research Fund, London (UK). Labs.

Description

The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of 220 kVp x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and vinblastine are not. (author)

Additional details

Identifiers

DOI
10.1038/bjc.1975.234;

Publishing Information

Journal Title
British Journal of Cancer
Journal Volume
32
Journal Issue
3
Series
Br. J. Cancer.
Journal Page Range
352-354
ISSN
0007-0920

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
7270593
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ALKYLATING AGENTS; ANIMAL CELLS; ANTIBODIES; BIOLOGICAL RADIATION EFFECTS; CHEMOTHERAPY; IMMUNE SERUMS; RADIOSENSITIZERS; RESPONSE MODIFYING FACTORS; X RADIATION
Descriptors DEC
ANTIMITOTIC DRUGS; BIOLOGICAL EFFECTS; DRUGS; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MEDICINE; RADIATION EFFECTS; RADIATIONS; THERAPY

Optional Information

Notes
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