Published September 1, 2003 | Version v1
Journal article Metadata-only

Tomographic optical breast imaging guided by three-dimensional mammography

Creators

  • 1. Department of Physics, Tufts University, Medford, Massachusetts 02155 (United States)
  • 2. Department of Electrical and Computer Engineering, Northeastern University, Boston, Massachusetts 02115 (United States)
  • 3. Department of Mathematics, Tufts University, Medford, Massachusetts 02155 (United States)
  • 4. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129 (United States)
  • 5. Breast Imaging Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114 (United States)

Description

We introduce a modified Tikhonov regularization method to include three-dimensional x-ray mammography as a prior in the diffuse optical tomography reconstruction. With simulations we show that the optical image reconstruction resolution and contrast are improved by implementing this x-ray-guided spatial constraint. We suggest an approach to find the optimal regularization parameters. The presented preliminary clinical result indicates the utility of the method

Additional details

Publishing Information

Journal Title
Applied Optics
Journal Volume
42
Journal Issue
25
Journal Page Range
p. 5181-5190
ISSN
0003-6935
CODEN
APOPAI

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
36025509
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ABSORPTION; BIOMEDICAL RADIOGRAPHY; IMAGE PROCESSING; IMAGES; MAMMARY GLANDS; SIMULATION; SPATIAL RESOLUTION; THREE-DIMENSIONAL CALCULATIONS; TOMOGRAPHY; X RADIATION
Descriptors DEC
BODY; DIAGNOSTIC TECHNIQUES; ELECTROMAGNETIC RADIATION; GLANDS; IONIZING RADIATIONS; MEDICINE; NUCLEAR MEDICINE; ORGANS; PROCESSING; RADIATIONS; RADIOLOGY; RESOLUTION; SORPTION

Optional Information

Notes
(c) 2003 Optical Society of America