Published July 1985 | Version v1
Journal article

Lack of effect of entorhinal kindling on L-[3H]glutamic acid presynaptic uptake and postsynaptic binding in hippocampus

  • 1. Univ. of Kentucky, Lexington

Description

Sodium-independent L-[3H]glutamic acid binding and sodium-dependent L-[3H]glutamic acid high affinity uptake were measured in hippocampal membranes of rats administered electroshock seizures or kindled to class 5 seizures by entorhinal cortical stimulation. There were no differences in these glutamatergic synaptic markers among electroshocked, kindled, or surgical control animals. Entorhinal kindling is not a reflection of activity-regulated facilitation of perforant path glutamatergic neurotransmission

Additional details

Publishing Information

Journal Title
Exp. Neurol.
Journal Issue
no.1
Series
Exp. Neurol.
ISSN
0014-4886
CODEN
EXNEA