Prognostic value of gated SPECT myocardial perfusion imaging in patients with coronary artery disease

213 patients with known or suspected CAD whom underwent gated SPECT myocardial perfusion imaging (MPI) in Department of Nuclear Medicine, 108 Central Military Hospital. Mean follow-up time was 14.6 ± 6.6 months. Patients with reversible defect and mixed defect had higher rate of cardiac events (43.4%) and revascularization (34.9%) than those with fixed defect (18.4% and 10.2%), respectively (p < 0.01; OR 3.4 - 4.7). The severity of myocardial perfusion defects was significantly correlated to wall motion, left ventricular function and cardiac events as well. Patients with WMS ≥ 2 and EF less than 40% had higher risk and heart failure, cardiac death rate than those with WMS <2 and EF < 40% (p < 0.05). Conclusions: In patients with known or suspected CAD, the characteristics of MPI are of high value in CAD prognosis. (author)