Published November 1980 | Version v1
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Hypoxic cell radiosensitizers and heavy charged particle radiations

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Description

The effect of hypoxic cell sensitizers such as metronidazole and misonidazole on the oxygen enhancement ratio (OER) in spread Bragg peaks is studied. There is a significant decrease in OER for all the sensitizers studied and for energy beam of heavy ions studied. In addition, with the sensitizers, there is little drop in OER with increasing LET

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Additional details

Publishing Information

Imprint Title
Biological and medical research with accelerated heavy ions at the Bevalac, 1977-1980
Journal Page Range
p. 87-88.
Report number
LBL--11220

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
12626816
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S43: PARTICLE ACCELERATORS;
Descriptors DEI
ANIMAL CELLS; ARGON; CARBON; COMPARATIVE EVALUATIONS; HAMSTERS; HELIUM; ION BEAMS; METRONIDAZOLE; MISONIDAZOLE; NEON; OXYGEN ENHANCEMENT RATIO
Descriptors DEC
ALCOHOLS; ANIMALS; ANTINEOPLASTIC DRUGS; AZOLES; BEAMS; DRUGS; ELEMENTS; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; IMIDAZOLES; MAMMALS; NITRO COMPOUNDS; NONMETALS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADIOSENSITIZERS; RARE GASES; RESPONSE MODIFYING FACTORS; RODENTS; VERTEBRATES