Imaging and quantitative analysis of regional cerebral blood volume by ring type SPECT

Regional cerebral blood volume (rCBV) was quantitatively measured in 13 healthy volunteers using SPECT with in vivo Tc-99m labeled erythrocytes. The rate of erythrocyte labeling was 97.3 +- 0.71 % for the first scanning and 97.6 +- 0.73 % for the second scanning, with relatively favorable stability. The boundary between the cerebral parenchyma and lateral ventricle was not seen; nor was the boundary seen between the cerebral cortex and white matter. The mean rCBV was 4.06 +- 0.55 (ml/100 g of brain). There was neither bilateral difference nor age-dependency in rCBV. Measurement of rCBV with SPECT may provide clinically important information. (Namekawa, K.)