Published February 2000
| Version v1
Journal article
Influence of low dose ionizing radiation on amplification and antitumor activity of LAK/TIL cells
- 1. Shandong Academy of Medical Sciences, Jinan (China). Inst. of Radiation Medicine
Description
Objective: To study the influence of low dose ionization on amplification and antitumor activity of LAK/TIL cells. Methods: TIL cells isolated from Lewis lung cancer tissues and LAK cells from spleen of tumor-bearing mouse were irradiated with different low doses of X-rays and were cultured after irradiation. Results: Low dose ionizing radiation improved the amplification volume of LAK/TIL cells, decreased the cell death ratio in amplification process, and increased the toxicity of LAK/TIL cells, Conclusions: Low dose ionizing radiation can result in amplification of biologically activated lymphocytes, and decreases the death ratio of the cells in amplification process
Additional details
Publishing Information
- Journal Title
- Chinese Journal of Radiological Medicine and Protection
- Journal Volume
- 20
- Journal Issue
- 1
- Journal Page Range
- p. 40-42
- ISSN
- 0254-5098
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 31032073
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CELL CULTURES; CELL PROLIFERATION; LOW DOSE IRRADIATION; LYMPHOCYTES; MICE; NEOPLASMS; SURVIVAL CURVES; X RADIATION
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DISEASES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; IRRADIATION; LEUKOCYTES; MAMMALS; MATERIALS; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES