Published 1986 | Version v1
Journal article Metadata-only

Effect of iodinated contrast media on human lymphocytes

Creators

  • 1. Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii, Obninsk (USSR)

Description

The mutagenic action of free Verografin as well as of Verografin contained in liposomes on cultures of lymphocytes from the peripheral blood of healthy donors was investigated for various concentrations. It was found, that free Verografin can induce damages of human lymphocytes already in clinical concentrations usually applicated. The probability of damages increased with the concentration. Verografin in liposomes had a lower cytogenic effect. (author)

Additional details

Additional titles

Original title (German)
Die Wirkung jodierter Roentgenkontrastmittel auf die Lymphozyten des Menschen

Publishing Information

Journal Title
Radiol. Diagn.
Journal Volume
27
Journal Issue
6
Series
Radiol. Diagn.
Journal Page Range
805-810
ISSN
0033-8354
CODEN
RDGNA

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
18013270
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
CHROMOSOMAL ABERRATIONS; CONTRAST MEDIA; LIPIDS; LYMPHOCYTES; MICROSPHERES; MITOTIC INDEX; ORGANIC IODINE COMPOUNDS; SIDE EFFECTS; SYNCHRONOUS CULTURES
Descriptors DEC
ANIMAL CELLS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CELL CULTURES; CONNECTIVE TISSUE CELLS; LEUKOCYTES; MATERIALS; MUTATIONS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; SOMATIC CELLS