Evaluation of regional cerebral blood flow using the CT 9800 xenon CBF imaging system

The measured values of the regional cerebral flow (r-CBF) changes by using a certain of measurement and data analysis methods. We studied the quantitative analysis of r-CBF using CT 9800 Xenon CBF Imaging System with a stable Xenon. The values of r-CBF are influenced by several input factors, i.e., the numbers of baseline scans, the image numbers of enhancement scans, the hematocrit values and smoothing methods. Using the acquired data from 20 patients, we evaluated the influences of those input factors. In the result, no significant difference in each of the mean values existed, the changes of those input factors produced variations of 1 to 10% in the calculated r-CBF. It is important for clinical estimations of r-CBF to recognize the fundamental parameters of the apparatus. (author)