Published February 1989
| Version v1
Journal article
Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells
- 1. National Cancer Institute, Bethesda, MD (USA)
Description
Only a few of the genes involved in DNA repair in mammalian cells have been isolated, and induction of a DNA repair gene in response to DNA damage has not yet been established. DNA polymerase beta (beta-polymerase) appears to have a synthetic role in DNA repair after certain types of DNA damage. Here we show that the level of beta-polymerase mRNA is increased in CHO cells after treatment with several DNA-damaging agents
Additional details
Publishing Information
- Journal Title
- Molecular and Cellular Biology
- Journal Volume
- 9
- Journal Issue
- 2
- Series
- Mol. Cell. Biol.
- Journal Page Range
- 851-853
- ISSN
- 0270-7306
- CODEN
- MCEBD
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21018731
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CELL CULTURES; CHO CELLS; DNA; DNA POLYMERASES; DNA REPAIR; MESSENGER-RNA; OVARIES; ULTRAVIOLET RADIATION
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; BODY; ELECTROMAGNETIC RADIATION; ENZYMES; FEMALE GENITALS; GONADS; NUCLEIC ACIDS; NUCLEOTIDYLTRANSFERASES; ORGANIC COMPOUNDS; ORGANS; PHOSPHORUS-GROUP TRANSFERASES; POLYMERASES; RADIATIONS; RNA; SOMATIC CELLS; TRANSFERASES