The preliminary results of treatment of solid tumors in children receiving nonstandard radiation therapy

Efficacy and toxicity-related results of non-standard irradiation used in the combined treatment of 129 children with solid tumors were evaluated in 1986-1993. Immediate response (complete or partial regression) was registered in 89.3% of cases of sarcoma of Ewing, 76.8% - rhabdomyosarcoma and 76.7% - other tumors. Local recurrence was observed in 4 and late onset complication of radiation injury in 10 patients. Actuarial 5-year survival was 54.3, 52.1 and 41.2% in Ewing sarcoma, rhabdomyosarcoma and other tumor groups, respectively