Application of insulin-like growth factor-I and insulin release test in diabetes mellitus
Creators
- 1. Radioimmunoassay Center of Qingdao Municipal Hospital, Qingdao (China)
Description
The purpose of this study was to determine the role of insulin-like growth factor-I (IGF-I) and insulin release test (IRT) in understanding the extent of damage to ability of reducing blood sugar in different types of diabetes mellitus (DM) and in selection of treatment plan and adjustment of using drugs. OGTT, IRT and determination of IGF-I level of 67 normal subjects and 217 DM patients were performed. The result was analyzed comparatively. The level of IGF-I was negatively correlated with the level of fasting blood sugar, and positively correlated with the level of fasting insulin. Our conclusions are: There are two ways of reducing blood sugar: one is by insulin, and the other is by IGF-I. IRT can reflect the former better, and IGF-I the latter. The combination of these two is of significant value in diagnosis and treatment of DM
Additional details
Publishing Information
- Journal Title
- Labeled Immunoassays and Clinical Medicine
- Journal Volume
- 10
- Journal Issue
- 3
- Journal Page Range
- p. 139-142
- ISSN
- 1006-1703
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 35089623
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CLINICAL TRIALS; COMPARATIVE EVALUATIONS; DATA COVARIANCES; DIABETES MELLITUS; DIAGNOSIS; GLUCAGON; GROWTH FACTORS; INSULIN; LIBERINS; PATHOGENESIS; PATHOLOGY; RADIOIMMUNOASSAY; STATISTICS; STH
- Descriptors DEC
- BIOASSAY; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE DISEASES; EVALUATION; HORMONES; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATHEMATICS; METABOLIC DISEASES; MITOGENS; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PEPTIDES; PITUITARY HORMONES; POLYPEPTIDES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; TESTING; TRACER TECHNIQUES