Published February 2003
| Version v1
Journal article
Mitochondrial control mechanism on apoptosis and ionizing radiation
Creators
- 1. Jilin Univ., Changchun (China). School of Public Health, MH Radiobiology Research Unit
Description
Mitochondria play a major role in apoptosis triggered by many stimuli. The various death signals induce directly and indirectly (through Bcl-2 family proteins) the increase of mitochondrial membrane permeability, the release of cytochrome c and the activation of caspases. The mechanisms that lead to this permeability are not yet completely understood. Here, authors review briefly the mechanisms of mitochondrial control during apoptosis and the possible effects of ionizing radiation in their mechanisms
Additional details
Publishing Information
- Journal Title
- Foreign Medical Sciences. Section of Radiation Medicine and Nuclear Medicine
- Journal Volume
- 27
- Journal Issue
- 2
- Journal Page Range
- p. 90-93
- ISSN
- 1001-098X
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 35080580
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- APOPTOSIS; CYTOCHROMES; IONIZING RADIATIONS; MEMBRANES; MITOCHONDRIA; PERMEABILITY; PROTEINS; RADIATION INJURIES; STIMULATION
- Descriptors DEC
- BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CELL CONSTITUENTS; DISEASES; INJURIES; ORGANIC COMPOUNDS; PHYSICAL PROPERTIES; PIGMENTS; PROTEINS; RADIATION EFFECTS; RADIATIONS