Management of Stage II glottic cancer

A detailed retrospective analysis was done of 55 patients with Stage II (TsNqMq) glottic cancer, treated at the University of Louisville Radiation Center from October 1953 to December 1975. Ninety-one percent of the patients were male. Eight-five percent of the patients had squamous cell carcinoma. The five year adjusted survival rate was 81% with a standard error of 5%. Twenty-seven percent of the patients had local failure and 58% of them were salvaged by further surgery. The median time to recurrence was eleven months. There was no case of laryngeal necrosis, and good function of the larynx was achieved in the majority of the patients. Eight second cancers were diagnosed during the continued follow-up of these patients. A brief review of the literature is included