3D-printing non-coplanar template assisted ¹²⁵I seed implantation for pelvic tumor: individual template design method

Objective: To compare the dosimetric data between preoperative plans and postoperative verification in computed tomography (CT)-guided and 3D-printing non-coplanar template-assisted ¹²⁵I seed implantation for pelvic tumor, and to explore the feasibility and accuracy of the personalized template designmethod. Methods: A total of 51 patients registered from Dec 2015 to Dec 2016 who were applied with 3D-printing guided template assisted radioactive seed implantations in the hospital were included in this study. A prescribed dose of 110-160 Gy was adopted. 3D-printing templates were designed and produced for 51 cases. The dosimetric parameters: D₉₀, minimum peripheral dose (mPD), V₁₀₀, V₁₅₀, V₂₀₀, conformal index (CI), external index (EI), and homogeneity index (HI) were compared between pre-and post-plans. Results: 51 cases' templates were in place well during the operations. Compared with the preoperative planning, the postoperative D₉₀, V₁₀₀, V₁₅₀, V₂₀₀, CI, EI and HI differences had no statistical difference (P > 0.05); mPD is larger than before (t = -2.96, P < 0.05). Conclusions: The main dosimetric parameters of postoperative verification were consistent well with the preoperative planning and have good accuracy, which could meet the clinical requirements. (authors)