Published March 2019
| Version v1
Journal article
The effect of diesel emission exposure on primary human bronchial epithelial cells from a COPD cohort: N-acetylcysteine as a potential protective intervention
Creators
- 1. The University of Queensland Thoracic Research Centre, The Prince Charles Hospital, Brisbane (Australia)
- 2. International Laboratory for Air Quality and Health, The Queensland University of Technology, Brisbane (Australia)
Description
Chronic obstructive pulmonary disease (COPD) will be the third leading cause of death world-wide by 2020. Prolonged exposure to particulate matter is associated with COPD progression and mortality. Diesel emissions are a major contributor to particulate matter pollution. In this study we test a therapeutic antioxidant, N-acetylcysteine (NAC), for its ability to protect bronchial epithelial cells (pHBECs) from patients with COPD from adverse effects of diesel emission exposure.
Additional details
Identifiers
- DOI
- 10.1016/j.envres.2018.12.035;
- PII
- S0013935118306649;
Publishing Information
- Journal Title
- Environmental Research
- Journal Volume
- 170
- Journal Page Range
- p. 194-202
- ISSN
- 0013-9351
- CODEN
- ENVRAL
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 55023834
- Subject category
- S54: ENVIRONMENTAL SCIENCES;
- Descriptors DEI
- AIR POLLUTION; ANTIOXIDANTS; DISEASES; EMISSION; HUMANS; MORTALITY; PARTICULATES; PATIENTS
- Descriptors DEC
- ANIMALS; MAMMALS; PARTICLES; POLLUTION; PRIMATES; VERTEBRATES
Optional Information
- Copyright
- Copyright (c) 2018 Elsevier Inc. All rights reserved.