Published November 1979 | Version v1
Journal article Metadata-only

Study of DNAase activity in thymus and bone marrow of irradiated rats

Creators

  • 1. Akademiya Meditsinskikh Nauk SSSR, Obninsk. Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii

Description

A study was made of alkaline and acid DNAase activity in thymocytes and bone marrow of rats. The activity of both acid and alkaline DNAase.s in thymocytes, 4 h after exposure in a dosage of 900 R, was more than two-fold increased as compared with that of bone marrow DNAases. It was shown that the increase of DNAase 1 activity in thymocytes is not followed by the decrease in DNAase 1 inhibitor activity. The rates of DNA enzymic degradation at different enzyme/substrate DNA ratio was determined to show that the increase in DNAase 1 activity in thymocytes of exposed rats is related to the increase in the active enzyme content of cells

Additional details

Additional titles

Original title (Russian)
Izuchenie aktivnosti DNKaz v timuse i kostnom mozge obluchennykh krys

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
24
Journal Issue
6
Series
Radiobiologiya.
Journal Page Range
803-807
ISSN
0033-8192

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
11543841
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
BONE MARROW CELLS; CATALYSIS; DNA-ASE; ENZYME INHIBITORS; EXPERIMENTAL DATA; GAMMA RADIATION; GRAPHS; MALES; METABOLISM; RADIATION DOSES; RATS; SUBSTRATES; TABLES; THYMOCYTES; TIME DEPENDENCE
Descriptors DEC
ANIMAL CELLS; ANIMALS; CONNECTIVE TISSUE CELLS; DATA; DATA FORMS; ELECTROMAGNETIC RADIATION; ENZYMES; ESTERASES; HYDROLASES; INFORMATION; IONIZING RADIATIONS; MAMMALS; NUMERICAL DATA; ORGANIC COMPOUNDS; PHOSPHATASES; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES

Optional Information

Notes
For English translation see the journal Radiobiology (USA).