Published December 2019 | Version v1
Journal article

Spleen phenotype in autosomal dominant polycystic kidney disease

  • 1. Department of Radiology, Weill Cornell Medicine, New York, NY (United States)
  • 2. Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai (China)
  • 3. Department of Medicine, Weill Cornell Medicine, New York, NY (United States)
  • 4. Rogosin Institute, New York, NY (United States)
  • 5. Department of Pathology, Weill Cornell Medicine, New York, NY (United States)
  • 6. Department of Healthcare Policy and Research, Weill Cornell Medicine, New York, NY (United States)
  • 7. Columbia College of Physicians and Surgeons, New York, NY (United States)

Description

Highlights: • Splenic cysts are unrelated to autosomal dominant polycystic kidney disease. • Height-adjusted Spleen Volume is 28% greater in ADPKD compared to controls. • Height-adjusted Spleen Volume may be a biomarker for ADPKD severity. • Spleen Length correlates with spleen volume in ADPKD patients. -- Abstract: To evaluate splenic phenotype in autosomal dominant polycystic kidney disease (ADPKD) including presence of cysts and splenomegaly to determine if these are ADPKD related or represent unrelated incidental findings.

Additional details

Identifiers

DOI
10.1016/j.crad.2019.08.015;
PII
S0009926019305306;

Publishing Information

Journal Title
Clinical Radiology
Journal Volume
74
Journal Issue
12
Journal Page Range
p. 975.e17-975.e24
ISSN
0009-9260
CODEN
CLRAAG

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55058861
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BIOLOGICAL MARKERS; CYSTS; KIDNEYS; PATIENTS; PHENOTYPE; SPLEEN; SPLENOMEGALY; UROGENITAL SYSTEM DISEASES
Descriptors DEC
BODY; DISEASES; ORGANS; PATHOLOGICAL CHANGES; SYMPTOMS

Optional Information

Copyright
Copyright (c) 2019 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.