Published December 1983
| Version v1
Journal article
Effect of pH on the formation of Tc(NaBH4)-MDP radiopharmaceutical analogues
- 1. Cincinnati Univ., OH (USA). Dept. of Chemistry
Description
Anion exchange high performance liquid chromatography has been employed to separate components of sup(99m)Tc(NaBH4)-MDP formulations prepared as a function of pH, the presence or absence of 99Tc carrier, and the presence or absence of air. The formulation pH is an effective variable for controlling the generation and interconversion of sup(99m)Tc-MDP components, and for allowing the preparation of large quantities of specific sup(99m)Tc-MDP complexes for biological evaluation. (author)
Additional details
Publishing Information
- Journal Title
- Int. J. Appl. Radiat. Isot.
- Journal Volume
- 34
- Journal Issue
- 12
- Series
- Int. J. Appl. Radiat. Isot.
- Journal Page Range
- 1577-1584
- ISSN
- 0020-708X
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 15035494
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- AIR; BOROHYDRIDES; CHEMICAL PREPARATION; ION EXCHANGE CHROMATOGRAPHY; LIGANDS; LIQUID COLUMN CHROMATOGRAPHY; OXIDATION; PERTECHNETATES; PH VALUE; PHOSPHONATES; RADIOPHARMACEUTICALS; REDUCTION; SODIUM COMPOUNDS; TECHNETIUM COMPLEXES; TECHNETIUM 99
- Descriptors DEC
- ALKALI METAL COMPOUNDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BORON COMPOUNDS; CHEMICAL REACTIONS; CHROMATOGRAPHY; COMPLEXES; DRUGS; FLUIDS; GASES; HOURS LIVING RADIOISOTOPES; HYDROGEN COMPOUNDS; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; OXYGEN COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES; SYNTHESIS; TECHNETIUM COMPOUNDS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPLEXES; TRANSITION ELEMENT COMPOUNDS; YEARS LIVING RADIOISOTOPES