The enhancement effects of xenon gas inhalation for the image analysis of the blood brain barrier damage

The enhancement study of the Iodide contained contrast material has been performed since Gado had presented its clinical application at the workshop on Reconstruction Tomography in 1975. In 1977, Winkler et al. reported the clinical utilization of Xenon gas enhancement study. However many literatures treated the partition coefficient and washout study of Xenon gas just like the radioactive Xenon-133. There are very few informations concerning the image analysis of Xenon enhanced CT. The image analysis of the reconstructed sagittal and coronal pictures with Xenon gas inhalation has been performed in this study. The ischemic small lesion of cerebral infarction is not usually identified in ordinary CT view. Three cases who had the T.I.A. of negative CT were clearly demonstrated in the reconstructed pictures with Xenon gas inhalation. And one case of left parietal glioma showed the partial negative image with Xenon gas CT among the slightly enhanced edema lesion. This part might be the infiltrating lesion of tumor. There are very few cases presented here, but the clinical application to detect the small lesion of cerebral parenchymal damage with Xenon gas inhalation might have some value and the image analysis study with the reconstruced sagittal and coronal view may have the role of detailed detection of small lesions. (author)