Published 1990 | Version v1
Journal article Metadata-only

Influence of different ALL therapies on height and growth rate

Creators

  • 1. Medizinische Akademie, Magdeburg (German Democratic Republic)
  • 2. Staedtisches Klinikum, Berlin-Buch (German Democratic Republic)

Description

Adult height in 20 patients, successfully treated for childhood leukemia, led to reduced height < 2 standard deviations (S.D.). The loss in projected final height of 0.8 S.D. was mainly due to intensity of maintenance therapy of protocol LSA2L2. In contrast, less intensive maintenance therapy (6-MP and MTX) of protocol BFM 81 showed a transient growth spurt. Final height equals projected target height. Neither 18 Gy nor 198Au intrathecally influenced final height. (author)

Additional details

Additional titles

Original title (German)
Einfluss unterschiedlicher ALL-Therapieprotokolle auf Koerperlaenge und Wachstumsgeschwindigkeit

Publishing Information

Journal Title
Paediatrie und Grenzgebiete
Journal Volume
29
Journal Issue
2
Series
Paediatr. Grenzgeb.
Journal Page Range
87-93
ISSN
0030-932X
CODEN
PAGRB

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
21071004
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BRAIN; CHEMOTHERAPY; CHILDREN; COBALT 60; DELAYED RADIATION EFFECTS; GAMMA RADIATION; GOLD 198; GROWTH; INHIBITION; LEUKEMIA; PATIENTS; RADIOTHERAPY
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CENTRAL NERVOUS SYSTEM; COBALT ISOTOPES; DAYS LIVING RADIOISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; GOLD ISOTOPES; HEAVY NUCLEI; HEMIC DISEASES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MAN; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NERVOUS SYSTEM; NUCLEI; ODD-ODD NUCLEI; ORGANS; PRIMATES; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; THERAPY; VERTEBRATES; YEARS LIVING RADIOISOTOPES