Published November 2019 | Version v1
Journal article Metadata-only

A simple decontamination procedure for unintended iodide impurity during [11C]methionine production

Creators

  • 1. Seoul National University Bundang Hospital, Seoul National University College of Medicine, Department of Nuclear Medicine (Korea, Republic of)
  • 2. Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Department of Nuclear Medicine (Korea, Republic of)

Description

A solid-phase extraction cartridge method is a widely used carbon-11 labeling method for obtaining [11C]methionine. Although the process is convenient and efficient, unintended impurity sometimes observed in the final product owing to contamination by volatile iodide generated during [11C]CH3I production. Herein, we suggest a simple method to eliminate impurities contained in [11C]methionine solution using an anion-exchange resin cartridge.

Additional details

Identifiers

DOI
10.1007/s10967-019-06757-6;

Publishing Information

Journal Title
Journal of Radioanalytical and Nuclear Chemistry
Journal Volume
322
Journal Issue
2
Journal Page Range
p. 933-939
ISSN
0236-5731
CODEN
JRNCDM

INIS

Country of Publication
Hungary
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
54121499
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CARBON 11; CONTAMINATION; DECONTAMINATION; EXTRACTION; IMPURITIES; IODIDES; IODINE; ION EXCHANGE; LABELLING; METHIONINE; METHYL IODIDE; RADIOPHARMACEUTICALS; RESINS; SOLIDS; SOLUTIONS; VOLATILITY
Descriptors DEC
AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CARBOXYLIC ACIDS; CLEANING; DISPERSIONS; DRUGS; ELEMENTS; EVEN-ODD NUCLEI; HALIDES; HALOGEN COMPOUNDS; HALOGENATED ALIPHATIC HYDROCARBONS; HALOGENS; HOMOGENEOUS MIXTURES; IODINATED ALIPHATIC HYDROCARBONS; IODINE COMPOUNDS; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; LIPOTROPIC FACTORS; MATERIALS; MINUTES LIVING RADIOISOTOPES; MIXTURES; NONMETALS; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANIC POLYMERS; ORGANIC SULFUR COMPOUNDS; PETROCHEMICALS; PETROLEUM PRODUCTS; POLYMERS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES

Optional Information

Copyright
Copyright (c) 2019 Akad#Latin Small Letter E With Acute#miai Kiad#Latin Small Letter O With Acute#, Budapest, Hungary