11C-Choline PET/CT and PSA kinetics
Creators
- 1. Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi, UO di Medicina Nucleare, PAD. 30, Bologna (Italy)
- 2. Policlinico S. Orsola-Malpighi, University of Bologna, Nuclear Medicine Unit, Bologna (Italy)
- 3. National Research Council (IBFM-CNR), Nuclear Medicine Unit, San Raffaele Scientific Institute, Institute for Bioimaging and Molecular Physiology, Milan (Italy)
Description
The role of PET/CT with radiolabelled 18F-choline or 11C-choline in patients with prostate cancer after primary treatment has not been established yet and there are no guidelines on the appropriate use of this emerging modality. According to the literature, choline PET/CT may have a role in restaging the disease in patients with biochemical relapse for the detection of local and/or lymph node and/or distant recurrence. The aim of this brief review is to summarize the results of the most relevant published studies with particular focus on the relationship between prostate-specific antigen levels and kinetics and the sensitivity of choline PET/CT for optimizing the selection of patients who may benefit the most from this diagnostic procedure, especially early after biochemical recurrence. (orig.)
Availability note (English)
Available from: http://dx.doi.org/10.1007/s00259-013-2377-zAdditional details
Identifiers
Publishing Information
- Journal Title
- European Journal of Nuclear Medicine and Molecular Imaging
- Journal Volume
- 40
- Journal Issue
- Suppl.1
- Series
- Prostate Cancer
- Journal Page Range
- p. 36-40
- ISSN
- 1619-7070
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 44105690
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ANTIGENS; BIOLOGICAL MARKERS; CARBON 11; CARCINOMAS; CHOLINE; COMPARATIVE EVALUATIONS; COMPUTERIZED TOMOGRAPHY; DIAGNOSIS; FLUORINE 18; LYMPH NODES; METASTASES; POSITRON COMPUTED TOMOGRAPHY; PROSTATE; RADIOPHARMACEUTICALS; RADIOTHERAPY; SPECIFICITY; TRACER TECHNIQUES; UPTAKE
- Descriptors DEC
- ALCOHOLS; AMMONIUM COMPOUNDS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBON ISOTOPES; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; EVALUATION; EVEN-ODD NUCLEI; FLUORINE ISOTOPES; GLANDS; HOURS LIVING RADIOISOTOPES; HYDROXY COMPOUNDS; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; LIPOTROPIC FACTORS; LYMPHATIC SYSTEM; MALE GENITALS; MATERIALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NANOSECONDS LIVING RADIOISOTOPES; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; QUATERNARY AMMONIUM COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOLOGY; THERAPY; TOMOGRAPHY