Published January 1, 1990 | Version v1
Journal article Metadata-only

The contribution of tunnelling to high values of kinetic isotope effect in aliphatic hydroxylation by a cytochrome P-450 model

Creators

  • 1. AN SSSR, Chernogolovka (USSR). Otdelenie Inst. Khimicheskoj Fiziki

Description

High values of kinetic isotope effect (KIE), up to 21.9 ± 1.9 at 200C, are obtained in cyclohexane oxidation by an iron tetramesitylporphyrin (TMPFeCl)-hypochlorite system; their very sharp dependence on temperature suggests tunnelling contribution to the C-H bond cleavage step. (author)

Additional details

Publishing Information

Journal Title
Journal of the Chemical Society (London), Chemical Communications
Journal Volume
1
Journal Issue
1
Series
J. Chem. Soc., Chem. Commun.
Journal Page Range
45-46
ISSN
0022-4936
CODEN
JCCCA

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
21042373
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
CATALYSIS; CYCLOHEXANE; HYDROXYLATION; IRON CHLORIDES; ISOTOPE EFFECTS; PORPHYRINS; TEMPERATURE DEPENDENCE
Descriptors DEC
ALKANES; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; CHLORIDES; CHLORINE COMPOUNDS; CYCLOALKANES; HALIDES; HALOGEN COMPOUNDS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HYDROCARBONS; IRON COMPOUNDS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; TRANSITION ELEMENT COMPOUNDS