Published November 1981
| Version v1
Journal article
Potentiation of radiation lethality in HeLa cells by mild hyperthermia and procaine
Description
Increased radiation lethality was observed in HeLa cells when irradiation was followed by two hours of incubation at 41/sup o/C in the presence of 1 mM procaine hydrochloride. The increase of radiation lethality produced by this combination was significantly higher than that produced by hyperthermia alone. Two hours of incubation with procaine at 37/sup o/C had no effect on the survival of irradiation cells
Additional details
Publishing Information
- Journal Title
- Radiology
- Journal Volume
- 141
- Journal Issue
- 2
- Series
- Radiology.
- Journal Page Range
- 533-535
- ISSN
- 0033-8419
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 13680118
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ANIMAL CELLS; BIOLOGICAL RADIATION EFFECTS; DOSE-RESPONSE RELATIONSHIPS; HELA CELLS; HYPERTHERMIA; IRRADIATION; PROCAINE; RADIOSENSITIVITY; RESPONSE MODIFYING FACTORS; TEMPERATURE DEPENDENCE
- Descriptors DEC
- ANESTHETICS; BIOLOGICAL EFFECTS; BODY TEMPERATURE; DRUGS; RADIATION EFFECTS