Bone-marrow imaging in pure red blood cell aplasia

Bone-marrow scintigraphy with indium chloride In-111 was performed on a patient with pure red blood cell aplasia before and after successful treatment with immunosuppressive drugs. The return of erythroid precursors to the bone marrow was accompanied by a substantial increase in the marrow uptake of 111In. The distribution of 111In in the posttreatment scan was indistinguishable from that of 52Fe. These results indicate that indium chloride In-111 is a useful agent for the delineation of erythroid cellularity within bone marrow