Published May 20, 1994 | Version v1
Journal article Metadata-only

General approach to the synthesis of specifically deuterium-labeled nucleosides

Creators

  • 1. Johns Hopkins Univ., Baltimore, MD (United States)

Description

Synthesis routes for labelled nucleosides starting with ribose have been studied. The method is viable for producing sufficient quantities of D/T labelled nucleosides for oligonucleotide synthesis. 1 tab

Additional details

Publishing Information

Journal Title
Journal of Organic Chemistry
Journal Volume
59
Journal Issue
10
Journal Page Range
p. 2715-2723.
ISSN
0022-3263
CODEN
JOCEAH

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
28027467
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
DEUTERIUM; DEUTERIUM COMPOUNDS; ISOTOPIC EXCHANGE; LABELLING; NUCLEOSIDES; REACTION INTERMEDIATES
Descriptors DEC
HYDROGEN COMPOUNDS; HYDROGEN ISOTOPES; ISOTOPES; LIGHT NUCLEI; NUCLEI; NUCLEOTIDES; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; RIBOSIDES; STABLE ISOTOPES