Quantitative regularities in occurrence of chromosome aberrations in the human lymphocyte culture affected by fractionated γ/neutron-irradiation at different stages of the mitotic cycle. Cytogenetic effect at stage S

Quantitative regularities of the chromosome aberrations yield in the human lymphocyte culture affected by fractionated γ/neutron-irradiation (in the direct and inverse sequences) at a stage of the replicative DNA synthesis(S), with the 1 to 5 h intervals between the dose fractions, were studied. The obtained results on the cytogenetic effect of interaction of damages were compared with those for the stages G0 and G1. In contrast to the latter cases, where occurrence of superadditive effects was high, only subadditive affects were observed for the stage S. 4 refs., 5 tabs