Application of radioisotopes in biochemistry of nucleic acids of viruses and bacteria

An attempt is made to systemize the data on the chemical (fermentative) methods of radionuclide tracer introduction into nucleic acids, and to determine the scope of problems arising in their practical application in laboratories. The description of the techniques is of practical orientation and leaves aside the in-depth mechanisms of the proceeding processes. The application of radionuclides in vive enabled the researchers to obtain information on the localization of molecules and structures in eucaryotic and procaryotic cells. The techniques are indespensable for the separation of biomolecules and purification of viruses, for investigations of metabolism in bodies and cell cultures. 383 refs.; 6 figs.; 3 tabs