Published July 1976 | Version v1
Journal article

Radioimmunoassay for vasopressin: plasma levels after stimulation by I-V nicotine injection

  • 1. Hopital de la Conception, 13 - Marseille (France)
  • 2. Aix-Marseille-2 Univ., 13 - Marseille (France)

Description

A radioimmunoassay for vasopressin which permits the estimation of plasma levels as low as 0.25μIU/ml was developed. The average plasma level of ADH after overnight water restriction was found to be 5.20μIU/ml. A hypersecretion of ADH was provoked by the intravenous injection of 1-2mg of nicotine. In 10 volunteer subjects this stimulation by nicotine provoked ADH secretion which reached a maximum between 2 and 15 minutes after injection; the hormone plasma level reached an average value of 21.3μIU/ml

Abstract (French)

On a realise un dosage radioimmunologique de la vasopressine (ADH) qui permet l'estimation d'un niveau plasmatique de 0,25μIU/ml. Le niveau moyen de l'ADH apres restriction hydrique etait de 5,20μIU/ml. On a provoque une hypersecretion d'ADH par injection intraveineuse de 1-2mg de nicotine. Chez 10 volontaires, cette stimulation par la nicotine a provoque une secretion d'ADH qui a atteint un maximum 2 a 15 minutes apres l'injection; le niveau plasmatique de l'hormone a atteint une valeur moyenne de 21,3μIU/ml

Additional details

Additional titles

Original title (French)
Dosage plasmatique radioimmunologique de la vasopressine: reponse a la stimulation par la nicotine

Publishing Information

Journal Title
Ann. Endocrinol. (Paris)
Journal Volume
37
Journal Issue
4
Series
Ann. Endocrinol. (Paris).
Journal Page Range
291-292

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
8303178
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
BLOOD PLASMA; RADIOIMMUNOASSAY; VASOPRESSIN
Descriptors DEC
BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; HORMONES; ISOTOPE APPLICATIONS; PEPTIDE HORMONES; PITUITARY HORMONES; TRACER TECHNIQUES