Published January 1989 | Version v1
Journal article

A case report of a thyroid papillary cancer that manifested leukocytosis and hypercalcemia after radiotherapy for bone metastasis

Description

Bone metastasis from a thyroid papillary cancer of a 59-year-old woman had been successfully treated with radiotherapy (6,000 rad) and iodine-131 (120 mCi). One year later, the patient developed leukocytosis (maximum 143,000/mm3) and hypercalcemia (16.0 mg/dl). A colony stimulating factor (CSF) was detectable in her plasma, and nude mice that had been given metastatic tissues sinilarly developed leukocytosis and hypercalcemia. Leukocytosis and hypercalcemia seemed to have been caused by the CSF produced in the bone metastasized tissues of this thyroid cancer. (author)

Additional details

Publishing Information

Journal Title
Gan No Rinsho
Journal Volume
35
Journal Issue
1
Series
Gan No Rinsho.
Journal Page Range
55-62
ISSN
0021-4949
CODEN
GANRA