Patient Specific Dosimetry in Radiosynovectomy ¹⁵³Sm-HA

Radiosynovectomy (RS) is an invasive procedure that causes ablation of the inflamed synovial tissue through the intra-articular injection of radiotracers. Hydroxyapatite labeled with Samarium-153 [¹⁵³Sm-HA] are one of the options of radiotracer in RS, especially in countries where its commercial availability is superior to other isotopes, p.e. ⁹⁰Y. ¹⁵³Sm emits β-particles with maximum energy of 808,2 keV and also a 103 keV γ-ray which is suitable to acquire images. Patient specific dosimetry for ¹⁵³Sm-HA RS can be a useful tool for individual treatment assessment and future determination of a standard injection activity. In the present work, we performed voxel dosimetry to calculate the 3D distribution of absorbed dose in four human articulations treated with ¹⁵³Sm-HA.