Published December 2019 | Version v1
Journal article Metadata-only

Whole solid tumour volume histogram analysis of the apparent diffusion coefficient for differentiating high-grade from low-grade serous ovarian carcinoma: correlation with Ki-67 proliferation status

Creators

  • 1. Department of Radiology, Jinshan Hospital, Fudan University, Shanghai 201508 (China)
  • 2. Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032 (China)
  • 3. Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai 200032 (China)
  • 4. Department of Medical Imaging, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163 (China)
  • 5. Department of Pathology, Obstetrics & Gynecology Hospital, Fudan University, Shanghai 200011 (China)
  • 6. Department of Radiology, Xinhua Hospital, Shanghai Jiao Tong University, Shanghai 200092 (China)
  • 7. Department of Radiology, Huashan Hospital North, Fudan University, Shanghai 201907 (China)
  • 8. Department of Radiology, Obstetrics & Gynecology Hospital, Fudan University, Shanghai 200011 (China)

Description

Highlights: • Most histogram metrics of ADC were significantly lower in HGSOC than in LGSOC. • The 75th showed the highest sensitivity and accuracy of 91.6% and 88.1%, respectively. • ADC histogram parameters showed a poor correlation with Ki-67 index. -- Abstract: To investigate whether apparent diffusion coefficient (ADC) histogram parameters based on whole solid tumour volume could differentiate high-grade (HGSOC) from low-grade serous ovarian carcinoma (LGSOC) and to correlate those parameters with the Ki-67 proliferation index.

Additional details

Identifiers

DOI
10.1016/j.crad.2019.07.019;
PII
S0009926019303630;

Publishing Information

Journal Title
Clinical Radiology
Journal Volume
74
Journal Issue
12
Journal Page Range
p. 918-925
ISSN
0009-9260
CODEN
CLRAAG

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55054847
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ACCURACY; BIOMEDICAL RADIOGRAPHY; CARCINOMAS; CORRELATIONS; METRICS; OVARIES; SENSITIVITY
Descriptors DEC
BODY; DIAGNOSTIC TECHNIQUES; DISEASES; FEMALE GENITALS; GONADS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIOLOGY

Optional Information

Copyright
Copyright (c) 2019 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.