Published September 1978
| Version v1
Journal article
Possible tumor localization of /sup 99m/Tc-labeled liposomes: effects of lipid composition, charge, and liposome size
- 1. Charing Cross Hospital, London
Description
The possible in vivo distribution of liposomes after they have been directly labeled with Tc-99m has been studied in rats bearing the Walker 256 carcinoma. The importance of lipid composition, charge, and size of liposome were studied with respect to possible tumor-localizing properties. Tumor uptake was best with small, fluid-membrane, negatively charged liposomes, as indicated by the distribution of the Tc-99m label. The uptake was visualized on scintigrams
Additional details
Additional titles
- Augmented title (English)
- Rats
Publishing Information
- Journal Title
- J. Nucl. Med.
- Journal Volume
- 19
- Journal Issue
- 9
- Series
- J. Nucl. Med.
- Journal Page Range
- 1049-1054
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 10445411
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BIOLOGICAL LOCALIZATION; CELL CONSTITUENTS; DISTRIBUTION; ISOMERIC NUCLEI; LABELLING; LIPOPROTEINS; NEOPLASMS; RATS; SCINTISCANNING; TECHNETIUM 99; TISSUES; UPTAKE
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIPIDS; MAMMALS; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; PROTEINS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RODENTS; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES