Published 2014
| Version v1
Book
Evaluation of radioprotective efficacy of pyrimidine-5-carboxylate derivative on radiation induced oxidative stress using Drosophila melanogaster
- 1. Department of Chemistry, P.A. College of Engineering, Mangalore (India)
- 2. Department of Chemistry, Mangalore University, Mangalore (India)
- 3. Microtron Centre, Department of Physics, Mangalore University, Mangalore (India)
Description
In the present study, radioprotection efficacy of Ethyl 4-(4-fluorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetra hydropyrimidine-5-carboxylate (PYR) was evaluated against the gamma ray induced oxidative stress using drosophila melanogaster (Oregon K). The gamma ray irradiated flies were assayed for oxidative stress markers namely; Thiobarbituric acid reactive substances (TBARS) and enzymatic antioxidant SOD and CAT. The oxidative stress was induced at 6 Gy. (author)
Additional details
Publishing Information
- Publisher
- Bhabha Atomic Research Centre
- Imprint Place
- Mumbai (India)
- ISBN
- 81-88513-61-X
- Imprint Title
- Proceedings of the DAE-BRNS twelfth biennial Trombay symposium on radiation and photochemistry
- Imprint Pagination
- 294 p.
- Journal Page Range
- p. 77-78
Conference
- Title
- 12. DAE-BRNS biennial Trombay symposium on radiation and photochemistry
- Acronym
- TSRP-2014
- Dates
- 6-9 Jan 2014
- Place
- Mumbai (India)
INIS
- Country of Publication
- India
- Country of Input or Organization
- India
- INIS RN
- 45103246
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BIOLOGICAL STRESS; DROSOPHILA; GAMMA RADIATION; PYRIMIDINES; RADIOPROTECTIVE SUBSTANCES
- Descriptors DEC
- ANIMALS; ARTHROPODS; AZINES; DIPTERA; DRUGS; ELECTROMAGNETIC RADIATION; FLIES; FRUIT FLIES; HETEROCYCLIC COMPOUNDS; INSECTS; INVERTEBRATES; IONIZING RADIATIONS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADIATIONS; RESPONSE MODIFYING FACTORS
Optional Information
- Notes
- 2 refs., 1 tab.