Late effects of heavy charged particles on the fine structure of the mouse coronary artery

Results reported here are from a pilot study conducted on mice sacrificed in connection with other experiments and from which tissues for electron microscopy were made available. Consequently, the range of radiation doses and particle species is limited. The objectives were to: (1) determine if late ultrastructural changes, estimated quantitatively, would be dose-dependent, and (2) provide preliminary information on LET-dependence so that future definitive experiments could be designed to measure both morphological and functional changes quantitatively