Published 1986 | Version v1
Journal article Metadata-only

Changes in the activity of some enzymes under the effect of Adeturon

Creators

  • 1. Meditsinska Akademiya, Sofia (Bulgaria). Nauchen Inst. po Rentgenologiya i Radiobiologiya

Description

The changes in the activity of lactate dehydrogenase (LDH), malate hydrogenase (MDH) and alkaline phosphatase (AP) were investigated in the blood serum of rats under the effect of the radioprotector Adeturon. Measurements was made at the 10th, 20th, 60th, 120th and 240th min after administration of the protector. It was observed that the changes in the activity of the tested enzymes differ in the time of their occurrence, direction, magnitude and duration. Most prolonged in time were changes in LDH activity. The data obtained are not sufficient to interpret the mechanism of the changes, but support the concept of the influence of the chemical radioprotection on cell metabolism

Additional details

Publishing Information

Journal Title
Problemi na Rentgenologiyata i Radiobiologiyata
Journal Volume
7
Series
Probl. Rentgenol. Radiobiol.
Journal Page Range
34-37
ISSN
0204-8019
CODEN
PRRAD

INIS

Country of Publication
Bulgaria
Country of Input or Organization
Bulgaria
INIS RN
20079081
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
ALKALINE PHOSPHATASE; BLOOD SERUM; ENZYME ACTIVITY; EXPERIMENTAL DATA; LACTATE DEHYDROGENASE; RADIATION PROTECTION; RADIOPROTECTIVE SUBSTANCES; RATS
Descriptors DEC
ANIMALS; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; DATA; DEHYDROGENASES; DRUGS; ENZYMES; ESTERASES; HYDROLASES; INFORMATION; MAMMALS; MATERIALS; NUMERICAL DATA; ORGANIC COMPOUNDS; OXIDOREDUCTASES; PHOSPHATASES; RESPONSE MODIFYING FACTORS; RODENTS; VERTEBRATES