Published November 9, 1987 | Version v1
Miscellaneous Restricted

Can bone metastases from mammary carcinomas and their regional distribution patterns established on the basis of radionuclide studies provide any clues to the mechanisms of their further spread over the skeletal system

Description

Retrospective analysis of data from 100 female patients showing metastisation from mammary carcinomas into the bones led to the conclusion that the vertrebral column must be a factor in the spread of those metastases to more remote skeletal regions. This is primarily explained by the role of the vertebral venous system and the special action of the red bone marrow that enhances the establishment of cells capable of metastisation. (TRV)

Availability note (English)

MF available from INIS under the Report Number.

Abstract (German)

Die retrospektive Studie von 100 Patientinnen mit Knochenmetastasen bei Mammacarcinom zeigt, dass der Vertebra eine Verteilerrolle bei der Metastasierung in andere Skelettregionen zugesprochen werden muss, und zwar primaer durch das vertebrale Venensystem und die guenstigen Bedingungen, die das rote Knochenmark fuer die Etablierung potentiell metastasierungsfaehiger Zellen bietet. (TRV)

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Additional details

Additional titles

Original title (German)
Koennen beim Mammacarcinom szintigraphisch nachgewiesene Knochenmetastasen und deren regionales Verteilungsmuster Auskunft ueber den Ausbreitungsmechanismus in das Skelettsystem geben?

Publishing Information

Imprint Pagination
98 p.
Report number
INIS-mf--12167