Published January 2018
| Version v1
Book
Influence of dose, age and smoking habit on somatic mutations in lymphocytes of individuals exposed to chronic low level natural radiation
- 1. Low Level Radiation Research Lab., Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Kollam (India)
- 2. Centre for Advanced Research in Physical Sciences, Fatima National College, Kollam (India)
- 3. Low Level Radiation Research Section, Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Mumbai (India)
Description
We have investigated the frequency of somatic cell mutations at the hypoxanthine-guanine phosphoribosyl transferase (HPRT) locus in human population from Kerala, in the south west coast of India. The T lymphocyte cloning assay was used to measure the frequency of somatic cell mutations. Thus, the present study has indicated that the natural radiation levels prevailing in the Kerala coast did not influence the somatic mutations at the HPRT locus. However, a statistically significant effect of age and smoking habit of the individuals on somatic cell mutations could be established
Additional details
Publishing Information
- Publisher
- Bhabha Atomic Research Centre
- Imprint Place
- Mumbai (India)
- Imprint Title
- Proceedings of the forty second annual conference of Environmental Mutagen Society of India and national conference on environmental mutagenesis: integration of basic biology and omics to improve human health - abstract book
- Imprint Pagination
- 162 p.
- Journal Page Range
- p. 87
Conference
- Title
- 42. annual conference of environmental mutagen society of India and national conference on environmental mutagenesis: integration of basic biology and omics to improve human health
- Acronym
- EMSI-2018
- Dates
- 25-27 Jan 2018
- Place
- Mumbai (India)
INIS
- Country of Publication
- India
- Country of Input or Organization
- India
- INIS RN
- 49091564
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; LYMPHOCYTES; RADIATION DOSES; RADIATION INDUCED MUTANTS; SOMATIC MUTATIONS; TOBACCO SMOKES
- Descriptors DEC
- AEROSOLS; ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; COLLOIDS; CONNECTIVE TISSUE CELLS; DISPERSIONS; DOSES; LEUKOCYTES; MATERIALS; MUTANTS; MUTATIONS; RADIATION EFFECTS; RESIDUES; SMOKES; SOLS; SOMATIC CELLS