Assessment of Framingham Risk Score and Serum Leptin in Patients with Skin Tag

Skin tags are common dermatological lesions that have been linked to metabolic syndrome, which includes diabetes, obesity, and hypertension, as well as cardiovascular disease. Increased adipose deposition and serum leptin levels may be associated with skin tags (STs). The relationship between serum lipid profile and serum leptin levels in patients with skin tags and the Framingham risk score was investigated. The Framingham risk score (FRS) is a method to calculate the likelihood of getting cardiovascular disease (CVD) during a 10-year period (CVD). The current study was carried out on 60 participants; 30 patients with STs and 30 apparently healthy as controls. Serum lipid profile and serum leptin were measured. There was Statistically significant difference of serum leptin level between skin tag (22.6+-16.4 ng/ml) group and control (13.23 +- 10.14 ng/ml) and cholesterol also showing significant difference between skin tag disease group (183.3 +- 37.12 mg/dl) and the control group (155.6 +- 21.86 mg/dl). Other parameters Low Density Lipoprotein (LDL), Triglycerides (TG) and non-High-Density Lipoprotein, cholesterol (non-HDL) show no significant difference between the two groups. An assessment was performed to differentiate between skin tag and Framingham risk score. It was found that 70% of patients are in high and moderate risk group. The present study found association between skin tag patients and Framingham risk score