Published November 1998 | Version v1
Journal article Metadata-only

Quantitative scintigraphic evaluation of molsidomine effect on myocardial bloodflow of coronary patients during exercise test

Creators

  • 1. SO RAMN, Tomskij Nauchnyj Tsentr, NII Kardiologii, Tomsk (Russian Federation)

Description

To assess changes in myocardial blood flow during exercise test after a single dose of molsidomine by a single-photon emission computer-aided tomography (SPECT) with 99mTc-methoxy-isobutyl-isonitrile (MIBI) was used. Fifteen coronary patients (men aged 46-62-years) are examined. It is shown that the calculation of regional myocardial blood flow permits assessing in absolute units blood supply to the myocardium in exercise test after drug therapy. In exercise, molsidomine significantly improves myocardial blood flow. In exercise, molsidomine significantly improves myocardial blood flow both in the poststenotic regions and in impact myocardium

Abstract (Russian)

Проведено количественное изучение изменений миокардиального кровотока при велоэргометрической нагрузочной пробе на фоне однократного приема молсидомина с помощью однофотонной эмиссионной компьютерной томографии (ОФЭКТ) с 99mTc-метокси-изобутил-изонитрилом (МИБИ). Обследовано 15 пациентов с ИБС. Показано, что техника количественного расчета регионального кровотока миокарда позволяет оценить в абсолютных единицах кровоснабжение миокарда при нагрузочных пробах, на фоне лекарственной терапии. Молсидомин достоверно улучшает миокардиальный кровоток при физической нагрузке как в постстенонических регионах, так и в интактном миокарде

Additional details

Additional titles

Original title (Russian)
Количественная сцинтиграфическая оценка влияния молсидомина на кровоток миокарда у пациентов с IBS при велоэргометрии

Publishing Information

Journal Title
Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost'
Journal Volume
43
Journal Issue
6
Journal Page Range
p. 28-35
ISSN
1024-6177
CODEN
MRRBE5

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
32017792
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BLOOD FLOW; CHEMOTHERAPY; CORONARIES; DYNAMIC LOADS; ISCHEMIA; MYOCARDIUM; PATIENTS; RADIOPHARMACEUTICALS; SCINTISCANNING; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TECHNETIUM 99
Descriptors DEC
ANEMIAS; ARTERIES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BLOOD VESSELS; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; HEART; HEMIC DISEASES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; MEDICINE; MUSCLES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SYMPTOMS; TECHNETIUM ISOTOPES; THERAPY; TOMOGRAPHY; VASCULAR DISEASES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
21 refs., 4 figs., 2 tabs.